February 14, 2019 – Public Awareness about Tetanus “It was concluded from the present study that Tetanus is a bacterial disease. It is not transmitted from parents to children, and there is no need for surgery, although medicines and vaccines can be given.”

June 5, 2017 – Polysaccharide conjugate vaccine protein carriers as a “neglected valency” – Potential and limitations (full text) ‘Tetanus toxin, which causes the clinical manifestations of tetanus, can be chemically inactivated to TT. This is used in vaccines against tetanus and as a protein carrier in conjugated polysaccharide vaccines (Table 1).”

December 20, 2016 – Vaccination of special populations: Protecting the vulnerable (full text) “Among the estimated 2 million pregnant women immunised in the US during the 2000–2003 influenza seasons, only 20 adverse events were reported to the CDC Vaccine Adverse Event Reporting System, of which 17 were minor injection-site or systemic reactions. There are fewer data on Td or Tdap uptake, due to the recent introduction of the vaccine for use during pregnancy and the fact that most of the global elimination campaigns have been carried out with tetanus toxoid vaccine. Nonetheless, a US study of 26,229 women vaccinated with Tdap matched with 97,265 unvaccinated women found no evidence of an increased risk of adverse obstetric events apart from a small increased risk of chorioamnionitis. Comment: I don’t see minor reactions here do you? Found 11 cases where Vaccine is FLU3 or TDAP and Symptom is Foetal death and Serious

September 1, 2015 – Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates ” (full text) ‘Tetanus toxin, which causes the clinical manifestations of tetanus, can be chemically inactivated to TT. This is used in vaccines against tetanus and as a protein carrier in conjugated polysaccharide vaccines (Table 1).”

November 14, 2013 – Motor palsies of cranial nerves (excluding VII) after vaccination: Reports to the US Vaccine Adverse Event Reporting System (full text) Cranial nerve palsies were reported after a wide variety of vaccines (Table 3). Most reports (43; 63%) listed a single vaccine. Among reports listing single vaccines, the most common vaccines were influenza vaccine seasonal trivalent inactivated, human papillomavirus vaccine quadrivalent, influenza H1N1 vaccine inactivated, and zoster vaccine live. Among reports listing multiple vaccines, the most common vaccines included hepatitis A vaccine; measles, mumps, and rubella vaccine live; diphtheria and tetanus toxoids and acellular pertussis vaccine; Hemophilus influenzae type b vaccine; and pneumococcal conjugate vaccine 7-valent. There was no conspicuous clustering of live or inactivated vaccines with palsies of particular cranial nerves.

February 2012 – Vaccine model of anti-phospholipid syndrome induced by tetanus vaccine. “Successful induction of anti-phospholipid syndrome (APS) in two different non-autoimmune prone mouse strains was achieved by tetanus toxoid (TTd) hyperimmunization using different adjuvants (glycerol or aluminium hydroxide), and different adjuvant pretreatments (glycerol or Complete Freund’s Adjuvant.” Comment: Anti-phospholipid syndrome (APS) is a disorder in which the immune system produces antibodies against certain normal proteins in your blood. The syndrome can cause blood clots in arteries, organs, such as your kidneys or lungs, or in veins, a condition known as deep vein thrombosis (DVT). APS can also cause pregnancy complications, such as miscarriages and stillbirths. This study documents that a tetanus shot can cause this syndrome in mice. Tetanus shots are routinely administered to women in 3rd World countries while they are pregnant. The VAERS database showed that in the two years preceding the CDC’s recommendation for all pregnant women to be vaccinated against influenza and H1N1, 7 miscarriages per year were reported as attributable to vaccination. In 2009, that number rose to 178. By using this formula, it was estimated that 1588 miscarriages (within a range of 946 to 3587) in 2009 were associated with pregnant mothers who were vaccinated with the H1N1 or combined influenza shot. I wonder if it was due to APS, and no one thought to look? The Mayo Clinic reports, “no cure for antiphospholipid syndrome, but medications can be effective in reducing your risk of blood clots.” No Cure? Don’t do things – like get a tetanus shot or a flu shot – to cause it in the first place!

October-December 2010 – Central nervous system inflammatory demyelinating disorders of childhood (full text) “Neurologic symptoms usually follow between 1 and 20 days of infectious illness or vaccination. Clinical spectrum of ADEM/CIS is wide with mild subclinical disease at one end and a fulminant presentation with seizure, coma and death secondary to hemorrhagic acute disseminated encephalomyelitis at the other end. It can involve cerebral hemisphere (hemiparesis, aphasia), brain stem (cranial nerve palsies, ataxia) and spinal cord (paraparesis with or without bowel and bladder involvement).”…“It is also associated with vaccination against influenza, measles, mumps, pertussis, tetanus, meningoccal disease, Japanese B, BCG and rabies; organ transplant and drugs like gold, serum administration.”

July-August 2010 – Prevalence of Antibodies Associated with Herd Immunity: A New Indicator to Evaluate the Establishment of Herd Immunity and to Decide Immunization Strategies “Results. The herd immunity was not established (p < pc) against measles, mumps, and varicella in schoolchildren aged 6 to 9 years, against measles in individuals aged 15 to 24 years, and against pertussis in all age groups. Based on these results, the measles-mumps-rubella (MMR) vaccine should be given to schoolchildren and individuals aged 15 to 24 years, the varicella vaccine to schoolchildren aged 6 to 9 years, and the diphtheria-tetanus-pertussis (DTaP/dTaP) vaccine to all age groups in order to establish the necessary herd immunity in the population.”

August 1997 – Severe but transient parkinsonism after tetanus vaccination (full text) Within a week he progressed to severe hypokinetic dysarthria, a mask-like face, and a resting tremor of both hands, and he had bradykinesia and generalised rigidity, together with a cogwheel phenomenon in the arms. … The tetanus vaccine used in our patient does not contain any living microorganisms. However, repeated injections with the tetanus toxoid might have caused hypersensitivity, and also an immunological cross reaction of antibodies with neuronal tissue directly after the last injection. This might also explain the pleiocytosis and raised protein and IgG content in CSF. The alternative explanation is that one of the substances in the vaccine vehicle, thiomersal or aluminium phosphate, had a neurotoxic effect.