Pathogens as adjuvants An adjuvant is a chemical or an ingredient used in a vaccine to enhance the production of antibodies. Adjuvants are broadly separated into two classes, based on their principal mechanisms of action; vaccine delivery systems and adjuvants that stimulate the immune response. Vaccine delivery systems are generally
PER.C6 Cell line The heart of the technology is the PER.C6 human cell line. This is a continuously dividing set of cells derived from a single human retina cell, immortalized using recombinant DNA technology. Like other continuous cell lines, PER.C6 cells can replicate indefinitely—but that is where the comparison ends. PER.C6 Technology
Pertussis, referred to as whooping cough, is an upper respiratory infection caused by the bacterium, Bordetella pertussis (written in studies as B. pertussis). Pertussis presents as a deep and harsh cough that is worse at night and does not include fever. While the infection usually lasts 6 weeks, the severity
September 30, 2019 – Phase 1 trial of a 20-valent pneumococcal conjugate vaccine in healthy adults “Systemic events (defined as fatigue, headache, chills, nausea/ vomiting, new muscle pain, aggravated muscle pain, new joint pain, and aggravated joint pain) were reported by a higher proportion of subjects in the PCV20 group (72.7%) compared to the Tdap group (57.6%) The
Pneumovax 23 – Pneumococcal Vaccine, Polyvalent Manufacturer: Merck & Co., Inc, – Indication: PNEUMOVAX 23 is indicated for vaccination against pneumococcal disease caused by those pneumococcal types included in the vaccine. PNEUMOVAX® 23 (pneumococcal vaccine polyvalent) package insert (pdf) INDICATION and Safety Information for Prevnar 13 Pneumococcal disease describes a group of infections
Polio is a viral infection that has been associated with varying degrees of paralysis. On March 26, 1953, American medical researcher Dr. Jonas Salk announced on a national radio show that he had successfully developed a vaccine against poliomyelitis. For promising eventually to eradicate the disease, which is known
Polio is a viral infection that has been associated with varying degrees of paralysis. On March 26, 1953, American medical researcher Dr. Jonas Salk announced on a national radio show that he had successfully developed a vaccine against poliomyelitis. For promising eventually to eradicate the disease, which is known
June 7, 2022 – Understanding the Role and Impact of Poly (Ethylene Glycol) (PEG) on Nanoparticle Formulation: Implications for COVID-19 Vaccines “The increased use of nanoparticles as contrast agents or in drug delivery, along with the introduction of mRNA vaccines encapsulated in PEGylated lipid nanoparticles has brought this issue to the
Polysorbate 80, also known as Tween80, is an amber-colored, viscous liquid with a slightly bitter taste. It is used primarily as an emulsifier in food products, cosmetics, vitamins, medicines, and vaccines. According to Emulsifiers.org, “When water and oil are mixed together and vigorously shaken, a dispersion of oil droplets in water
More and more vaccines are being recommended for pregnant women. And to think, less than 10 years ago, we would not even recommend a Tylenol or anti-histamine to someone who is pregnant! This is not a good suggest. Everything that goes into the mother has the potential for causing a